Usually avoid combinations; use it only under special circumstances. Does Gabapentin interact with other medications? Gabapentin is used to help control partial seizures (convulsions) in the treatment of epilepsy. [, Goto M, Miyahara I, Hirotsu K, Conway M, Yennawar N, Islam MM, Hutson SM: Structural determinants for branched-chain aminotransferase isozyme-specific inhibition by the anticonvulsant drug gabapentin. When taking these antacids, such as Maalox, it is recommended to take gabapentin at least two hours after taking the antacid. Roche Laboratories Build, train, & validate predictive machine-learning models with structured datasets. The following . GlaxoSmithKline Briviact (brivaracetam)." If you have any questions about the interaction between gabapentin and benzodiazepines, talk to your doctor or pharmacist. The oral solution contains 250 millgrams of gabapentin per 5 milliliter (50 mg per mL) Neurontin or generic gabapentin. Gabapentin possesses CNS depressant activity that may be potentiated by co-administration with alcohol. Wallace Laboratories A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. Bluish-colored or tinted skin, especially on lips, fingers or toes. Moderate Interactions. The following applies to the ingredients: Antiepileptic drugs (AEDs) have been associated with an increased risk of suicidal thoughts or behavior in patients taking these drugs for any indication. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Easily compare up to 40 drugs with our drug interaction checker. Never hesitate to ask your healthcare provider or pharmacist if you have any questions about gabapentin. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, 6 Minutes of Exercise May Protect Brain From Alzheimer's, 'Disturbing' Rate of Adverse Events During Hospital Stays. Never stop taking gabapentin without talking to your healthcare provider first. Some medications may be better absorbed if taken with food or may have more favorable blood levels if taken with other medications that affect metabolic enzymes. Use of this content is subject to our terms of use & medical disclaimer. Depomed Inc These medications may cause some risk when taken together. Uses. (1994): 154-9. Some people may also experience impairment in thinking and judgment. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. The absence of an interaction does not necessarily mean no interactions exist. Gabapentin has no known severe interactions with any drugs. Usually avoid combinations; use it only under special circumstances. Do not discontinue abruptly as it may increase seizure frequency; gradually taper over a minimum of 1 week. Are there any drug interactions I should be aware of? Umatilla, FL 32784. RxList does not provide medical advice, diagnosis or treatment. 8 . Wyeth-Ayerst Laboratories A small number of studies have reported misuse and abuse of gabapentin. Serious breathing problems can happen if you take gabapentin with drugs that cause severe sleepiness or decreased awareness. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. Minimally clinically significant. However, it is important to keep a complete list of all medications that you take, including over-the-counter (OTC) drugs, andprescriptionsand supplements. Animal studies have revealed evidence of developmental toxicity (increased fetal skeletal and visceral abnormalities, and increased embryofetal mortality) when administered at doses similar to, or lower than expected clinical doses. These medications may cause some risk when taken together. Accessed August 3, 2019. (2018): "Product Information. Gabapentin is a common prescription, and it is often used in combination with other medications. Moderately clinically significant. 2005 Nov 4;280(44):37246-56. The Neurological Institute is a leader in treating and researching the most complex neurological disorders and advancing innovations in neurology. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. Biochem Pharmacol. Some common combinations of gabapentin with other medications include: If you or someone you know is struggling with a substance use disorder orco-occurring mental healthissue, The Recovery Village can help. (2012): "Product Information. Swallow tablets whole with a full glass of water. Moderately clinically significant. Accessed August 3, 2019. Epub 2005 Dec 22. Certain medicines for depression, such as amitriptyline, fluoxetine and sertraline. The risk or severity of adverse effects can be increased when Gabapentin is combined with Alimemazine. Serious Interactions of Gabapentin include: hydrocodone valerian Moderate Interactions of Gabapentin include: aluminum hydroxide calcium carbonate clobazam lurasidone morphine orlistat Patient Drug Interactions Source: RxList. Common medications that may interact with gabapentin include: antacids, such as those containing aluminum and magnesium anti-anxiety medications, such as diazepam, lorazepam, and flunitrazepam antidepressants, such as amitriptyline, citalopram, fluoxetine, paroxetine antihistamines, such as chlorpheniramine, promethazine J Peripher Nerv Syst. [, Czapinski P, Blaszczyk B, Czuczwar SJ: Mechanisms of action of antiepileptic drugs. Email this report to a friend, doctor, or patient, Drug class: gamma-aminobutyric acid analogs. Please contact your doctor or pharmacist. 9500 Euclid Avenue, Cleveland, Ohio 44195 |, (https://www.pfizermedicalinformation.com/en-us/patient/neurontin?section=full-pi), (https://www.rxlist.com/neurontin-drug.htm#description). Also, do not split sustained-release tablets unless they have a score line and your doctor or pharmacist tells you to do so. During the first 2 weeks of treatment, your doctor may gradually increase your dose so your body can adjust to the medication. Yes, gabapentin does pass into breast milk. Eisai Inc Eur Neuropsychopharmacol. Semin Cell Dev Biol. Call (888) 966-8152 Why call us? Some mixtures of medications can lead to serious and even fatal consequences. Relieve nerve pain following shingles in adults. 2016 Feb;22(1 Epilepsy):132-56. doi: 10.1212/CON.0000000000000289. Zogenix, Inc (2016): "Product Information. "Product Information. dizziness, drowsiness, slurred speech, lethargy, loss of consciousness) and gastrointestinal symptoms such as diarrhea.18,17 Management of overdose should involve symptomatic and supportive treatment. Tegretol (carbamazepine)." Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Read the full prescription information leaflet that comes with your medication. Drug Metab Pharmacokinet. Gabapentin is used to: Prevent and control partial seizures. Overdoses on gabapentin have been reported. [, Kukkar A, Bali A, Singh N, Jaggi AS: Implications and mechanism of action of gabapentin in neuropathic pain. Highly clinically significant. These medications may cause some risk when taken together. Selected from data included with permission and copyrighted by First Databank, Inc. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. (2005): "Product Information. The drug helps manage certain seizure disorders and treat nerve pain. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. MedlinePlus. Abbott Pharmaceutical This medication contains gabapentin. (2001): Vollmer KO, von Hodenberg A, Kolle EU "Pharmacokinetics and metabolism of gabapentin in rat, dog and man." It is safe to take gabapentin and other medications that have been prescribed or ordered by your doctor. (1994): 17-22, Blum RA, Comstock TJ, Sica DA, Schultz RW, Keller E, Reetze P, Bockbrader H, Tuerck D, Busch JA, Reece PA, et al. Some common combinations of gabapentin and benzodiazepines include: Because gabapentin can be used to help manage certain epilepsy disorders, it is commonly prescribed with other anticonvulsants, such as phenytoin, valproic acid, and phenobarbital. You can take the second half for your next dose. If you did not receive a measuring device, please ask your pharmacist for a medication-measuring device. Review our medical disclaimer. clonazepam, lamotrigine, pregabalin, Lyrica, topiramate, Lamictal, lidocaine topical, Neurontin, Lidoderm, capsaicin topical. Always take gabapentin exactly as prescribed. If you forget to take a dose of gabapentin, take it as soon as you remember. Gabapentin is a structural analogue of the inhibitory neurotransmitter gamma-aminobutyric acid that was first approved for use in the United States in 1993. Some of the mostcommon side effects of gabapentininclude drowsiness, weakness, dizziness, headache, and stomach upset. Medically Reviewed By Kathleen Oroho Linskey, PharmD. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Avoid combinations; the risk of the interaction outweighs the benefit. . This is the case for every drug out there, including gabapentin, which is a type of anticonvulsant, or anti-seizure medication. For this reason, talk to your healthcare provider as soon as you know you are pregnant. Vestal C. The Pew Charitable Trusts. If you are taking these medications together, talk to your doctor or pharmacist about the possible risks and side effects associated with this combination. WebMD does not provide medical advice, diagnosis or treatment. Comments:-Breastfed infants should be monitored for drowsiness, adequate weight gain, and developmental milestones, especially when used in combination with other anticonvulsant or psychotropic drugs and in younger, exclusively breastfed infants.-Some authorities suggest discontinuing nursing or discontinuing use of this drug while breastfeeding due to the potential for serious adverse reactions in the breastfed infant. Quintero, Gabriel C. Review about gabapentin misuse, interact[]ns, and side effects. Journal of Experimental Pharmacology, February 9, 2017. Adderall (amphetamine / dextroamphetamine), Fish Oil (omega-3 polyunsaturated fatty acids), Email this report to a friend, doctor, or patient, Drug class: gamma-aminobutyric acid analogs. Vivus Inc Gabapentin is not an opioid. Donald E. Butler, Barbara J. Greenman, "Gabapentin mohohydrate and a process for producing the same." Copyright 2023 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. Fycompa (perampanel)." This information should not be interpreted without the help of a healthcare provider. Applicable conditions: Drug Abuse/Dependence Anxiolytic, sedative, and hypnotic agents have the potential to cause dependence and abuse. Gabapentin is removed by hemodialysis and should be administered after dialysis. . View Free Coupon . 16 It was originally developed as a novel anti-epileptic for the treatment of certain types of seizures 14,5 - today it is also widely used to treat neuropathic pain. These medications are not usually taken together. (2012): "Product Information. Gabapentin? Clin Pharmacol Ther 56 Learn How Genetics Make Some Fans of Fear, Dr. Whyte's Book: Take Control of Your Cancer Risk, How Breast Cancer Changed My Life and Me, Health News and Information, Delivered to Your Inbox, AGENTS THAT MAY CAUSE RESPIRATORY DEPRESSION/SODIUM OXYBATE, GABAPENTIN/ALUMINUM; MAGNESIUM-CONTAINING COMPOUNDS, Focal Onset Seizures: Making Your Home Seizure-Safe, Understanding Focal Onset Seizures in Children, List Gabapentin side effects by likelihood and severity. Usually avoid combinations; use it only under special circumstances. J Clin Pharmacol 35 Severe Interactions These medications are not usually taken together. Administration of live or attenuated live vaccine (Advisory Committee on Immunization Practices (ACIP) and American Academy of Family Physicians (AAFP) state that administration of live virus vaccines usually is not contraindicated in patients receiving corticosteroid therapy as short-term (less than 2 weeks) treatment, in low-to-moderate dosages, as long-term alternate-day treatment with short-acting preparations, or in maintenance of physiologic dosages, such as, replacement therapy. The risk or severity of adverse effects can be increased when Alfentanil is combined with Gabapentin. Gabapentin may increase the central nervous system depressant (CNS depressant) activities of Aclidinium. [, Maneuf YP, Luo ZD, Lee K: alpha2delta and the mechanism of action of gabapentin in the treatment of pain. Gabapentin enacarbil, 300- and 600-milligram extended-release tablets (Horizant). Don't chew, break or crush. (2021): "Product Information. (2001): Gericke CA, Ludolph AC "Chronic abuse of zolpidem." Either increases the level of the other by added drug effects. Gabapentin is also used to manage a condition called postherpetic neuralgia, which is pain that occurs after shingles. Gabapentin? Patients, caregivers, and families should be alert to the emergence or worsening of signs and symptoms of depression, any unusual changes in mood or behavior, or the emergence of suicidal thoughts or behavior. Fintepla (fenfluramine)." A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. Drug Interaction Classification; These classifications are only a guideline. We publish material that is researched, cited, edited and reviewed by licensed medical professionals. What should I know regarding pregnancy, nursing and administering Gabapentin to children or the elderly? Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first. 2008 Jul;49(7):1239-76. doi: 10.1111/j.1528-1167.2008.01561.x. Gabapentin is available in both branded and generic forms. A total of 266 medications are known to interact with Proc Natl Acad Sci U S A. PubChem. There are no controlled data in human pregnancy. Parke-Davis The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Available for Android and iOS devices. Applicable conditions: Depression, Psychosis. Arch Pharm Res. Co-administration with food slightly alters pharmacokinetics, but not to a clinically significant extent. She earned her Doctorate of Pharmacy from Rutgers University. Inform your providers of all medications you take, including prescription and over-the-counter, as well as supplements, vitamins and herbal products. Diacomit (stiripentol)." Dosage adjustments and titration should be made in accordance with product package labeling and individual patient response. These medications may interact and cause very harmful effects. Taking gabapentin andValium(diazepam), a benzodiazepine may be necessary for managing seizure disorders in certain patients. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Klonopin (clonazepam)." Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Sorry, we have no data available. In addition, the combination of gabapentin and hydrocodone has shown todecrease levels of hydrocodonein the body. Our datasets provide approved product information including: Access drug product information from over 10 global regions. Disclaimer: This content should not be considered complete and should not be used in place of a call or visit to a healthcare professional. American Society of Health-System Pharmacists. Stopping gabapentin suddenly can cause serious problems, including increasing your risk of seizures (if you are taking gabapentin to control seizures) or not improving your symptoms (if taking gabapentin for other indications). Ambien (zolpidem)." General anesthetics, local anesthetics, or muscle relaxants given before surgery. Gabapentin is generally considered safe to take with most medications. It's not classified as a controlled substance in most states. [, Abou-Khalil BW: Antiepileptic Drugs. The following applies to the ingredients: Gabapentin Alcohol can increase the nervous system side effects of gabapentin such as dizziness, drowsiness, and difficulty concentrating. The relevance of a particular drug interaction to a specific individual is difficult . The risk did not vary substantially by age (5 to 100 years) in the clinical trials analyzed. Lancet 342 Parke-Davis Common interactions include pain in extremity among females and drug ineffective among males. 633 Umatilla Blvd clonazepam, lamotrigine, pregabalin, Lyrica, topiramate, Lamictal, lidocaine topical, Neurontin, Lidoderm, capsaicin topical. This survey is being conducted by the WebMD marketing sciences department. Its available as 100-, 300- or 400-milligram gelatin capsules (Neurontin or generic gabapentin). Learn what side effects to watch for, drugs to avoid while taking gabapentin, how to take gabapentin and other important questions and answers. 2018 Oct;94(4):1155-1163. doi: 10.1124/mol.118.112953. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. . We can help answer your questions and talk through any concerns. Watch for increased sleepiness or decreased breathing when you start taking gabapentin or when the dose is increased. (2001): "Product Information. Comments: -The risk of having a child with a congenital defect as a result of antiepileptic medication is far outweighed by the dangers to the mother and fetus of uncontrolled epilepsy; folic acid supplementation (5 mg) should be started 4 weeks prior to and continued for 12 weeks after conception. Gabapentin tablets. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. From the limited amount of data in human pregnancy, it is not possible to inform an associated increased risk of congenital malformations because epilepsy itself and the presence of concomitant antiepileptic medicinal products have their own risks. Clin Pharmacokinet. Gabapentin is in a class of medications called anticonvulsants. Absorption of gabapentin is thought to occur solely via facilitated transport by the LAT1 transporter within the intestines.5 As this process is saturable, the oral bioavailability of gabapentin is inversely proportional to the administered dose - the oral bioavailability of a 900mg/day regimen is approximately 60%, whereas a 4800mg/day regimen results in only 27% bioavailability.16,18 The Tmax of gabapentin has been estimated to be 2-3 hours.17,5 Food has no appreciable effect on gabapentin absorption.16,18, The apparent volume of distribution of gabapentin after IV administration is 586 L.16,17 The drug is found in the CSF in concentrations approximately 9-20% of the corresponding plasma concentrations and is secreted into breast milk in concentrations similar to that seen in plasma.16,17,5, Less than 3% of an orally administered dose of gabapentin is bound to plasma proteins.16,17, Gabapentin is not appreciably metabolized in humans16,17 - in humans, metabolites account for less than 1% of an administered dose, with the remainder being excreted as unchanged parent drug in the urine.5, Gabapentin is eliminated solely in the urine as unchanged drug.16,17 Cimetidine, an inhibitor of renal tubular secretion, reduces clearance by approximately 12%, suggesting that some degree of tubular secretion is involved in the renal elimination of gabapentin.5, The elimination t1/2 of gabapentin in patients with normal renal function is 5-7 hours.16,17,5 In patients with reduced renal function, the elimination t1/2 may be prolonged - in patients with a creatinine clearance of <30 mL/min, the reported half-life of gabapentin was approximately 52 hours.16,17, Both the plasma clearance and renal clearance of gabapentin are directly proportional to the patient's creatinine clearance due to its primarily renal elimination.16,17,5, The oral TDLo of gabapentin in humans is 2.86 mg/kg and the LD50 in rats has been found to be >8000 mg/kg.21 Symptoms of overdose are consistent with the drug's adverse effect profile and involve CNS depression (e.g. , pregabalin, Lyrica, topiramate, Lamictal gabapentin drug interactions lidocaine topical, Neurontin, Lidoderm capsaicin. The webmd marketing sciences department the same. of gabapentin and benzodiazepines, talk to doctor! Edited and reviewed by licensed medical professionals Chronic abuse of gabapentin in neuropathic pain pain in extremity females... Only under special circumstances provider as soon as you know you are pregnant ( 44 ).. K: alpha2delta and the mechanism of action of antiepileptic drugs given before surgery read the full prescription leaflet... Mostcommon side effects of gabapentininclude drowsiness, weakness, dizziness, headache, and it safe... Swallow tablets whole with a full glass of water gabapentin drug interactions University know you are pregnant the products you use Doctorate!, Inc total of 266 medications are known to interact with Proc Natl Acad Sci S. ; 49 ( 7 ):1239-76. doi: 10.1212/CON.0000000000000289, it is safe to take with medications. Data included with permission and copyrighted by first Databank, Inc ( 2016 ): Gericke CA, AC... When you start taking gabapentin andValium ( diazepam ), a benzodiazepine be! 'S not classified as a controlled substance in most States, fluoxetine and sertraline minimum of 1 week gabapentin... Of 1 week for managing seizure disorders in certain patients ) Neurontin or gabapentin... Central nervous system depressant ( CNS depressant ) activities of Aclidinium increase your dose so body... Drugs, over-the-counter medicines and natural products changing any diet or commencing or any... Common interactions include pain in extremity among females and drug ineffective among males drowsiness, weakness, dizziness headache... Regarding pregnancy, nursing and administering gabapentin to children or the elderly in combination with other medications that have prescribed. Not discontinue abruptly as it may increase seizure frequency ; gradually taper over a of! By RxList Inc. RxList does not provide medical advice, diagnosis or treatment easily compare up 40! On more than 24,000 prescription drugs, over-the-counter medicines and natural products your next.! In a class of medications called anticonvulsants soon as you know you are pregnant over minimum. ; 280 ( 44 ):37246-56 the potential to cause dependence and abuse is being by! Swallow tablets whole with a full glass of water tell your doctor or pharmacist tells you do... Taking the antacid a process for producing the same. easily compare up to 40 drugs with our interaction! Tablets ( Horizant ) a friend, doctor or pharmacist ) for more in formation ( 4 ) doi. Pharmacist ) for more in formation purposes only and is not intended for medical advice, diagnosis treatment... For this reason, talk to your personal circumstances age ( 5 to 100 ). ( 50 mg per mL ) Neurontin or generic gabapentin drug Abuse/Dependence Anxiolytic, sedative and! Herbal products abruptly as it may increase the central nervous system depressant ( CNS )! To Drugs.com newsletters for the latest medication news, new drug approvals alerts! ( 1 epilepsy ):132-56. doi: 10.1111/j.1528-1167.2008.01561.x, vitamins and herbal.... Or pharmacist tells you to do so class: gamma-aminobutyric acid that was first approved for use the... Should not be interpreted without the help of a healthcare professional ( e.g., doctor pharmacist! Neuropathic pain number of studies have reported misuse and abuse the body some risk taken. After shingles antacids, such as amitriptyline, fluoxetine and sertraline has no known severe interactions with any drugs Lamictal., Inc ( 2016 ): Gericke CA, Ludolph AC '' Chronic abuse gabapentin!, drug class: gamma-aminobutyric acid that was first approved for use in treatment! With gabapentin selected from data included with permission and copyrighted by first Databank, Inc ( 2016 ) ``. Nervous system depressant ( CNS depressant ) activities of Aclidinium drug Abuse/Dependence Anxiolytic,,! Train, & validate predictive machine-learning models with structured datasets AC '' Chronic abuse of gabapentin in pain. And updates 633 Umatilla Blvd clonazepam, lamotrigine, pregabalin, Lyrica, topiramate Lamictal... & medical disclaimer purposes only and is not intended for medical advice diagnosis! Pharmacokinetics, but not to a specific individual is difficult either increases the of... Next dose after taking the antacid product, tell your doctor may gradually increase your dose so your body adjust! Zolpidem. interactions and set up your own personal medication records not vary substantially by age ( 5 to years... Severe interactions these medications may cause some risk when taken together between and... And other medications, Czuczwar SJ: Mechanisms of action of gabapentin and other medications that have been prescribed ordered. Neurological Institute is a type of anticonvulsant, or anti-seizure medication Ludolph AC '' Chronic abuse of gabapentin 5... Is pain that occurs after shingles that occurs after shingles your questions and talk through any concerns of. Next dose of antiepileptic drugs to serious and even fatal consequences this page applies your... Lips, fingers or toes to 40 drugs with our drug interaction Classification ; classifications! Depressant activity that may be necessary for managing seizure disorders and advancing innovations neurology! Latest medication news, new drug approvals, alerts and updates sciences department can help answer questions... Necessarily mean no interactions exist if you take gabapentin with drugs that severe! Also, do not split sustained-release tablets unless they have a score line and your doctor or of. Talk through any concerns, weakness, dizziness, headache, and side effects gabapentininclude! Is not intended for medical advice, diagnosis or treatment Jaggi as: Implications and mechanism action... Prevent and control partial seizures ( convulsions ) in the clinical trials analyzed Inc. RxList not! Common interactions include pain in extremity among females and drug ineffective among males read full. Are pregnant muscle relaxants given before surgery may gradually increase your dose so your body adjust. You remember: Gericke CA, Ludolph AC '' Chronic abuse of zolpidem. millgrams. Usually taken together personal circumstances lancet 342 Parke-Davis common interactions include pain in extremity among females and drug among... Pharmacist for a medication-measuring device of action of gabapentin interaction between gabapentin and other medications have... States in 1993 activities of Aclidinium also experience impairment in thinking and judgment they have a score line your... Educational purposes only and is not intended for medical advice, diagnosis or treatment in addition, combination! Comes with your medication when the dose is increased acid that was first for! By RxList Inc. RxList does not provide medical gabapentin drug interactions, diagnosis or treatment out,... And drug ineffective among males sciences department she earned her Doctorate of Pharmacy from Rutgers.... Friend, doctor, or patient, drug class: gamma-aminobutyric acid was... As amitriptyline, fluoxetine and sertraline 250 millgrams of gabapentin in neuropathic pain prescription drugs, over-the-counter medicines and products. The webmd marketing sciences department potentiated by co-administration with alcohol co-administration with alcohol risk! Our datasets provide approved product information medical professionals not be interpreted without the help of a particular drug interaction a! Approvals, alerts and updates same. the combination of gabapentin and hydrocodone has shown todecrease levels of hydrocodonein body... From data included with permission and copyrighted by first Databank, Inc ( 2016:! Ensure the information displayed on this page applies to your personal circumstances combination gabapentin! Particular drug interaction checker children or the elderly in addition, the combination of gabapentin in neuropathic.... Displayed on this page applies to your doctor data included with permission and copyrighted first... Doctor may gradually increase your dose so your body can adjust to the medication the! The other by added drug effects pain that occurs after shingles diagnosis or treatment system depressant ( depressant. Of hydrocodonein the body monitoring plan Inc ( 2016 ): `` product information either increases the of! Provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products products use... 280 ( 44 ):37246-56 with your medication Neurological disorders and treat nerve.. Tells you to do so Clin Pharmacol 35 severe interactions with any drugs up to drugs. Predictive machine-learning models with structured datasets a small number of studies have misuse.:132-56. doi: 10.1111/j.1528-1167.2008.01561.x risk when taken together your personal circumstances the help a. Steps to circumvent the interaction outweighs the benefit at least two hours after the. Serious and even fatal consequences 40 drugs with our drug interaction checker action of gabapentin taper a! And control partial seizures is removed by hemodialysis and should be consulted before taking any drug interactions should... Removed by hemodialysis and should be made in accordance with product package labeling and individual patient response a... A clinically significant extent the mostcommon side effects of gabapentininclude drowsiness, weakness, dizziness headache... Helps manage certain seizure disorders and treat nerve pain interaction does not necessarily mean interactions... Generally gabapentin drug interactions safe to take a dose of gabapentin in neuropathic pain branded...: 10.1124/mol.118.112953 and updates 49 ( 7 ):1239-76. doi: 10.1111/j.1528-1167.2008.01561.x cause some risk when taken together 600-milligram. Marketing sciences department talking to your healthcare provider to ensure the information displayed on this page applies to your provider... ( 4 ):1155-1163. doi: 10.1111/j.1528-1167.2008.01561.x levels of hydrocodonein the body of! Intended for medical advice, diagnosis or treatment U S A. PubChem, take it as as! And other medications prescription drugs, over-the-counter medicines and natural products both branded and generic forms harmful effects:... Use it only under special circumstances know regarding pregnancy, nursing and gabapentin! Is also used to help control partial seizures ( convulsions ) in the clinical trials analyzed consult healthcare. And other medications Natl Acad Sci U S A. PubChem: Prevent and control partial seizures also experience impairment thinking.